Search on: SINGLE-STRAND SPECIFIC DNA AND RNA ENDONUCLEASES 
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Descriptor English:   Single-Strand Specific DNA and RNA Endonucleases 
Descriptor Spanish:   Endonucleasas Específicas del ADN y ARN con un Solo Filamento 
Descriptor Portuguese:   Endonucleases Específicas para DNA e RNA de Cadeia Simples 
Tree Number:   D08.811.277.352.335.350.700
D08.811.277.352.355.325.700
D08.811.277.352.355.350.820
D08.811.277.352.700.350.025
Definition English:   Enzymes that catalyze the endonucleolytic cleavage of single-stranded regions of DNA or RNA molecules while leaving the double-stranded regions intact. They are particularly useful in the laboratory for producing "blunt-ended" DNA molecules from DNA with single-stranded ends and for sensitive GENETIC TECHNIQUES such as NUCLEASE PROTECTION ASSAYS that involve the detection of single-stranded DNA and RNA
History Note English:   2009(1990) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24528 
Unique Identifier:   D015719 

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